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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Bulletin of Semashko National Research Institute of Public Health</journal-id><journal-title-group><journal-title>Bulletin of Semashko National Research Institute of Public Health</journal-title></journal-title-group><issn publication-format="print">2415-8410</issn><issn publication-format="electronic">2415-8429</issn><publisher><publisher-name>FSSBI «N.A. Semashko National Research Institute of Public Health»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1530</article-id><article-categories><subj-group subj-group-type="heading"><subject>Обзорная статья</subject></subj-group></article-categories><title-group><article-title>MAIN TRENDS IN THE EVALUATION OF HEALTHCARE TECHNOLOGIES IN THE WORLD IN THE PERIOD FROM 1980 TO 2020: LITERATURE REVIEW</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Meshkov</surname><given-names>D. O</given-names></name><bio></bio><email>dmitrymeshkov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Bezmelnitsyna</surname><given-names>L. Yu</given-names></name><bio></bio><email>blyu18@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Cherkasov</surname><given-names>S. N</given-names></name><bio></bio><email>cherkasovsn@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Spasennikova</surname><given-names>M. G</given-names></name><bio></bio><email>mspasennikova@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff id="aff-1">V.A. Trapeznikov Institute of Control Sciences</aff><aff id="aff-2">Federal Scientific and Clinical Center for Children and Adolescents</aff><aff id="aff-3">N.A. Semashko National Research Institute of Public Health</aff><pub-date date-type="epub" iso-8601-date="2021-12-16" publication-format="electronic"><day>16</day><month>12</month><year>2021</year></pub-date><issue>2</issue><fpage>16</fpage><lpage>25</lpage><history><pub-date date-type="received" iso-8601-date="2022-04-08"><day>08</day><month>04</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2021,</copyright-statement><copyright-year>2021</copyright-year></permissions><abstract>The article considers the development of health technology assessment: it reflects the dynamics of the introduction the technology assessment agencies into the healthcare decision-making system from 1980 to 2020. It was established that during the study period 60 organizations were created in 31 countries of the world. An analysis of the dependence of expert structures on the level of domestic gross product revealed that in 75% of countries with low per capita domestic gross product, there are no organizations evaluating health technologies. At average and above average levels, 50 per cent or more countries have the agencies, and in some cases the functions are distributed among several organizations. The study also examined the evolution of the applied methods, it was found that initially many countries used cost minimization methods and introduced thresholds of the indicator of readiness to pay into the system of decision-making on financing, while during the studied period there is the change from rigid evaluation criteria to multidisciplinary evaluation approaches.</abstract><kwd-group xml:lang="en"><kwd>assessment of healthcare technologies</kwd><kwd>gross domestic product</kwd><kwd>methods of clinical and economic analysis</kwd><kwd>the willingness to pay threshold</kwd><kwd>Multicriteria decision analysis</kwd><kwd>HTA Core Model ®</kwd><kwd>HTA Core Model ®</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>оценка технологий здравоохранения</kwd><kwd>валовый внутренний продукт</kwd><kwd>методы клинико-экономического анализа</kwd><kwd>порог готовности платить</kwd><kwd>мультикритериальный дисперсный анализ</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Хабриев Р.У. 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