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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Bulletin of Semashko National Research Institute of Public Health</journal-id><journal-title-group><journal-title>Bulletin of Semashko National Research Institute of Public Health</journal-title></journal-title-group><issn publication-format="print">2415-8410</issn><issn publication-format="electronic">2415-8429</issn><publisher><publisher-name>FSSBI «N.A. Semashko National Research Institute of Public Health»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1598</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>STATE POLICY DURING THE FIRST CHOLERA EPIDEMIC IN RUSSIA</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Semashko</surname><given-names>N. A</given-names></name><bio></bio><email>egorysheva@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">National Research Institute of Public Health</aff><pub-date date-type="epub" iso-8601-date="2022-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2022</year></pub-date><issue>1-2</issue><fpage>160</fpage><lpage>165</lpage><history><pub-date date-type="received" iso-8601-date="2022-04-08"><day>08</day><month>04</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2022,</copyright-statement><copyright-year>2022</copyright-year></permissions><abstract>Historical epidemiology helps to model the processes of elimination of infectious diseases, to predict their spread. The article is devoted to the history of the fight against the Cholera epidemic in the Russian Empire. Cholera was first introduced from Asia to Europe in the early nineteenth century. The fight against the first cholera epidemic in Russia (1823) was quite successful due to timely anti-epidemic measures taken by the government, medical community. The next epidemic (1829-1931) affected most of European Russia and caused a high level of morbidity and mortality. The Government's actions during this period were extremely inconsistent. The fight against the epidemic was carried out by police measures. The doctors' opinions were ignored. Quarantines that were contrary to the interests of foreign trade were often lifted. Large cities and capitals with poor sanitary conditions have suffered the most from the epidemic. In 1831, the epidemic spread beyond the borders of Russia. Russian doctors have contributed to the study of the epidemiology of cholera. They formulated provisions on the contagiousness of cholera, the importance of people in its spread, and the need to create antiepidemic barriers.</abstract><kwd-group xml:lang="en"><kwd>history of medicine</kwd><kwd>cholera epidemic</kwd><kwd>antiepidemic measures</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>история медицины</kwd><kwd>эпидемия холеры</kwd><kwd>противоэпидемические мероприятия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>About the Cholera discovered in Astrakhan (Cholera morbus). Voenno-medicinskij zhyrnal [Military Medical Journal]. 1824. No. 1. P. 75-83 (in Russian).</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Nastavlenie o lechenii bolezni, nazyvaemoj holera (Cholera morbus), izdannoe Medicinskim sovetom [The Manual on the treatment of the disease called Cholera (Cholera morbus), published by the Medical Council]. 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