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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Bulletin of Semashko National Research Institute of Public Health</journal-id><journal-title-group><journal-title>Bulletin of Semashko National Research Institute of Public Health</journal-title></journal-title-group><issn publication-format="print">2415-8410</issn><issn publication-format="electronic">2415-8429</issn><publisher><publisher-name>FSSBI «N.A. Semashko National Research Institute of Public Health»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1602</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>OUTSTANDING CONTRIBUTION OF ACADEMICIAN P.A. VERSHILOVA TO THE VACCINE PREVENTION OF BRUCELLOSIS</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Kulakov</surname><given-names>Yuri Konstantinovich</given-names></name><bio></bio><email>ykulakov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Ivanov-Pryanichnikov</surname><given-names>Igor Andreevich</given-names></name><bio></bio><email>ivig4@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Gamaleya National Center of Epedimiology and Microbiology</aff><pub-date date-type="epub" iso-8601-date="2022-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2022</year></pub-date><issue>1-2</issue><fpage>182</fpage><lpage>191</lpage><history><pub-date date-type="received" iso-8601-date="2022-04-08"><day>08</day><month>04</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2022,</copyright-statement><copyright-year>2022</copyright-year></permissions><abstract>The article is dedicated to Academician of the USSR Academy of Medical Sciences, Doctor of medical sciences, professor Polina A. Vershilova - the world-class scientist whose scientific interests were in the field of vaccine prevention and control of brucellosis in the Soviet Union and a number of countries. The early scientific works of P.A. Vershilova with colleagues at the Gamaleya Institute of Epidemiology and Microbiology are shown for the experimental development and industrial production the world's first live vaccine used to prevent human brucellosis since 1952 to now. The works of P.A. Vershilova and colleagues to study the safety and efficacy of a brucellosis chemical vaccine for use in immunoprophylaxis of human brucellosis are presented. The creative versatile activity of P.A. Vershilova, as a talented organizer of public health in the field of epidemiology and vaccine prevention of human brucellosis and infectious diseases, as a wonderful and rare teacher is reviewed. The scientific achievements of the outstanding microbiologist, epidemiologist and the world's first creator of a live vaccine against human brucellosis - Academician P.A. Vershilova currently are highly appreciated by the state in the name of square in front of the Gamaleya National Research Center for Epidemiology and Microbiology.</abstract><kwd-group xml:lang="en"><kwd>history of medicine</kwd><kwd>Polina A. Vershilova</kwd><kwd>brucellosis</kwd><kwd>epidemiology</kwd><kwd>live vaccine</kwd><kwd>brucellosis chemical vaccine</kwd><kwd>immunoprophylaxis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>история медицины</kwd><kwd>Полина Альбертовна Вершилова</kwd><kwd>бруцеллез</kwd><kwd>эпидемиология</kwd><kwd>живая вакцина</kwd><kwd>бруцеллезная химическая вакцина</kwd><kwd>иммунопрофилактика</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Бруцеллез. Труды экспедиции ВИЭМ по изучению овечьего бруцеллеза (1933-1936) / под. ред. П.Ф. Здродовского. М.: Всесоюзный институт экспериментальной медицины, 1937. С. 455.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Вершилова П.А. Способ иммунизации людей против бруцеллеза козье-овечьего типа. Авторское свидетельство № 105579.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Zdrodowski P., Vershilova P., Kotlarova H. Immunological research on brucellosis and human Immunization against this infection by means of an attenuated live vaccine // The Journal of Infectious Diseases. 1957. Vol. 101, no. 1. P. 1-7.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Vershilova P.A. The use of live vaccine for vaccination of human beings against brucellosis in the USSR // Bull World Health Organ. 1961. Vol. 24. P. 85-89.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Вершилова П.А. Живая вакцина против бруцеллеза // Профилактика инфекций живыми вакцинами. М.: Мед-гиз, 1960. С. 270-302.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Вершилова П.А., Голубева А.А. Бруцеллез в СССР и пути его профилактики. М.: Медицина, 1970. 189 с.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Вершилова П.А., Чернышева М.И., Князева Э.Н. Патогенез и иммунология бруцеллеза. М.: Медицина, 1974. 272 с.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Вершилова П.А., Драновская Е.А. Способ получения антигена. Авторское свидетельство № 467933.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Вершилова П.А., Ельшина Г.А., Драновская Е.А. и др. Сравнительное изучение безвредности и реактогенности различных дозировок бруцеллезной химической вакцины при ревакцинации людей // Журнал микробиологии, эпидемиологии и иммунобиологии. 1985. № 11. С. 56-60.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Вершилова П.А. Активная иммунизация против бруцеллеза: дис.. д-ра мед. наук. М.: Институт эпидемиологии и микробиологии имени Н.Ф. Гамалеи АМН СССР, 1949. 480 с.</mixed-citation></ref></ref-list></back></article>
