Bulletin of Semashko National Research Institute of Public HealthBulletin of Semashko National Research Institute of Public Health2415-84102415-8429FSSBI «N.A. Semashko National Research Institute of Public Health»273710.25742/NRIPH.2024.01.022Обзорная статьяIvanP. Pavlov is a scientist who made a scientific revolutionIsakovaValeriya G.isakova@nriph.ruhttps://orcid.org/0009-0003-6711-4416N. A. Semashko National Research Institute of Public Health1603202428114314625042025Copyright © 2025,2025<p>The article is devoted to the analysis of I.P.Pavlov's contribution to the development of world science. His role in the introduction of new methodological approaches to the study of the human organism, in the development of techniques allowing to conduct long-term experiments on practically healthy animals, due to which a breakthrough in understanding the functioning of the digestive system occurred, is considered. Imperfect knowledge in the field of digestive system was corrected, supplemented and enriched by I.P.Pavlov with new important data. The world scientific community highly appreciated the Russian scientist's contribution to science, awarding him the Nobel Prize in 1904.</p>Ivan PavlovA chronic experimentPhysiology of the digestive tractNobel Prize in Physiology and MedicineПавловхронический экспериментфизиология пищеварительного трактаНобелевская премия по физиологии и медицине1.Stepin V.S., Stochik A.M., Zatravkin S.N. History and Philosophy of Medicine. Scientific revolutions in medicine XVII- XXI centuries. Moscow: Academic Project; 2020. 20—25. (in Russian)2.3.Bernard K. Course of general physiology. Life phenomena common to animals and plants. Transl. from French. — St. Petersburg: Publishing HouseI.I. Bilibin; 1878. 3—5. (in Russian)4.5.Pavlov I.P. Lectures on the work of the main digestive glands. Moscow, Leningrad: eds. Acad. of Sciences of the USSR; 1949. 36. (in Russian)6.7.PavlovI.P. Nobel lecture / In the book: Nobel Prizes. Physiology and Medicine. Vol.I. M., ID «Nobel Lectures in Russian»; 2006; vol. I. 212—233. (in Russian)8.9.Bernard K. Course of general physiology. Life phenomena common to animals and plants. Transl. from French. St. Petersburg, Publishing HouseI.I. Bilibin; 1878. 295, 302. (in Russian)