Bulletin of Semashko National Research Institute of Public HealthBulletin of Semashko National Research Institute of Public Health2415-84102415-8429FSSBI «N.A. Semashko National Research Institute of Public Health»299710.25742/NRIPH.2023.01.005Научная статьяRisk factors for reproductive losses of the population of the Magadan regionPavlovYaroslav N.pyn5552007@yandex.ruSavvinaNadezhda V.nadvsavvina@mail.ruM. K. Ammosov North-Eastern Federal University, Yakutsk, Russia151220231293416102025Copyright © 2023,2023The article identifies the main types of factors affecting the growth of reproductive losses of the population. Based on the survey data, the main risk factors among respondents that could serve as predictors of the growth of reproductive losses and the occurrence and development of internal fetal malformations were identified and analyzed. An increase in the risks of reproductive losses was found in the presence of genetic disorders in close relatives, due to the age of a pregnant woman of 35 or more years and in the presence of psychoemotional overload. Anatomical abnormalities of the uterine structure and immune-hormonal disorders were identified as key medical factors. The main demographic and socio-behavioral risk factors of socially determined risks of reproductive losses and high levels of their prevalence have been identified. The results obtained were correlated to determine the odds ratio between individual risk factors and were used as the basis for creating a prognostic model of risk factors for reproductive losses of the population of residents of the Magadan region.reproductive losses, risk factors of productive losses, prognostic model, biomedical factors, demographic factors, socio-behavioral factors, surveyрепродуктивные потери, факторы рискарепродуктивных потерь, прогностическая модель, медико-биологические факторы, демографические факторы, социо-поведенческие факторы, опрос1.S. C. Lean, H. Derricott, R. L. Jones et al. Advanced maternal age and adverse pregnancy outcomes: A systematic review and meta-analysis. PLoS One. 2017;12(10):e0186287.2.Лисицын Ю. П. Общественное здоровье и здравоохранение. М.: Медицина; 2002. 416 с.3.Адушев М. Н. Демография и экономика России: зависимость, проблемы и возможности их решения. Региональная экономика и управление: электронный научный журнал. 2021;68(4):41.4.С. В. Андронов, А. А. Лобанов, А. И. Попов и др. Репродуктивные потери у коренных жителей Арктической зоны Западной Сибири. Сбережение коренного населения в Арктической зоне РФ в условиях трансформации образа жизни и изменения климата, Архангельск, 24—25 мая 2018 года. 2018. С. 100—102.5.Губина О. В., Проворова А. А. Роль инноваций в решении демографических проблем Арктики: опыт изучения восприятия населением. Арктика и Север. 2021;(44):130—157.6.Атapбaeвa B. Ш. К вопросу гинекологической заболеваемости женщин репродуктивного возраста. Вестник Казахского национального медицинского университета. 2020;(1):1—4.7.Yatsenko A. N., Turek P. J. Reproductive genetics and the aging male. J Assist Reprod Genet. 2018;35(6):933—941.