Bulletin of Semashko National Research Institute of Public HealthBulletin of Semashko National Research Institute of Public Health2415-84102415-8429FSSBI «N.A. Semashko National Research Institute of Public Health»302610.25742/NRIPH.2023.04.012Научная статьяTrends and priorities of clinical science in Russia in 2020—2022AlshevskayaAlina A.alkkina@yandex.ruAksenovaElena I.eiak@yandex.ruState Budgetary Institution «Research Institute for Healthcare Organization and Medical Management of Moscow Healthcare Department», Moscow, Russian FederationSechenov First Moscow State Medical University, Moscow, Russian FederationPeoples' Friendship University of Russia named after Patrice Lumumba, Moscow, Russian Federation151220234717620102025Copyright © 2023,2023Clinical science in Russia is in constant development, and the period from 2020 to 2022 is characterized by a number of important trends and priorities. These directions are largely due to global changes in the structure of healthcare, medical care and the focus of attention of researchers around the world in connection with the COVID-19 pandemic. This review considers several key areas that determine the future development of medicine in the world and in the country: digital medicine and technological integration, personalized predictive medicine, artificial intelligence in medicine, as well as changing the concept of quality of life and recognizing the primary role of psycho-social impacts in the structure providing medical care.trends in medicinedigitalizationinterdisciplinary researchcoronavirus infectionpersonalized predictive medicineartificial intelligence in medicinepandemicCOVID-19тренды в медицинецифровизациямеждисциплинарные исследованиякоронавирусная инфекцияперсонализированная предиктивная медицинаискусственный интеллект в медицинепандемияCOVID-19Massetti M, Chiariello GA. The metaverse in medicine. Eur Heart J Suppl. 2023;25(Suppl B):B104-B107. doi: 10.1093/eurheartjsupp/suad083Wilmes N, Hendriks CWE, Viets CTA, Cornelissen SJWM, van Mook WNKA, Cox-Brinkman J, Celi LA, Martinez-Martin N, Gichoya JW, Watkins C, Bakhshi-Raiez F, Wynants L, van der Horst ICC, van Bussel BCT. Structural under-reporting of informed consent, data handling and sharing, ethical approval, and application of Open Science principles as proxies for study quality conduct in COVID-19 research: a systematic scoping review. BMJ Glob Health. 2023;8(5):e012007. doi: 10.1136/bmjgh-2023-012007Maxwell L, Shreedhar P, Levis B, Chavan SA, Akter S, Carabali M. Overlapping research efforts in a global pandemic: a rapid systematic review of COVID-19-related individual participant data meta-analyses. BMC Health Serv Res. 2023;23(1):735. doi: 10.1186/s12913-023-09726-8Liu ZY, Huang Y, Xu J, Xiang L, Su ZH, Liu YW, Zhang H. Analysis and prediction of research hotspots and trends in pediatric medicine from 2,580,642 studies published between 1940 and 2021. World J Pediatr. 2023;19(8):793—797. doi: 10.1007/s12519-023-00731-9Almubarak H. The Potential Role of Telemedicine in Early Detection of Oral Cancer: A Literature Review. J Pharm Bioallied Sci. 2022;14(Suppl 1):S19-S23. doi: 10.4103/jpbs.jpbs_641_21Dhediya R, Chadha M, Bhattacharya AD, Godbole S, Godbole S. Role of Telemedicine in Diabetes Management. J Diabetes Sci Technol. 2023;17(3):775—781. doi: 10.1177/19322968221081133Khanijahani A, Akinci N, Quitiquit E. A Systematic Review of the Role of Telemedicine in Blood Pressure Control: Focus on Patient Engagement. Curr Hypertens Rep. 2022;24(7):247—258. doi: 10.1007/s11906-022-01186-5Ma Q, Sun D, Tan Z, Li C, He X, Zhai Y, Wang L, Cui F, Li M, Gao J, Wang L, Zhao J. Usage and perceptions of telemedicine among health care professionals in China. Int J Med Inform. 2022;(166):104856. doi: 10.1016/j.ijmedinf.2022.104856Bouabida K, Lebouché B, Pomey MP. Telehealth and COVID-19 Pandemic: An Overview of the Telehealth Use, Advantages, Challenges, and Opportunities during COVID-19 Pandemic. Healthcare (Basel). 2022;10(11):2293. doi: 10.3390/healthcare10112293Moses JC, Adibi S, Shariful Islam SM, Wickramasinghe N, Nguyen L. Application of Smartphone Technologies in Disease Monitoring: A Systematic Review. Healthcare (Basel). 2021;9(7):889. doi: 10.3390/healthcare9070889Becker B, Gadzhiev N, Popiolek M, Gross AJ, Netsch C. Smartphone-App für Patienten mit Nierensteinen [A mobile app for patients suffering from kidney stones]. Urologe A. 2018;57(5):577—582. doi: 10.1007/s00120-018-0652-0Sarkies MN, Bowles KA, Skinner EH, Mitchell D, Haas R, Ho M, Salter K, May K, Markham D, O'Brien L, Plumb S, Haines TP. Data collection methods in health services research: hospital length of stay and discharge destination. Appl Clin Inform. 2015;6(1):96—109. doi: 10.4338/ACI-2014-10-RA-0097Lu L, Zhang J, Xie Y, Gao F, Xu S, Wu X, Ye Z. Wearable Health Devices in Health Care: Narrative Systematic Review. JMIR Mhealth Uhealth. 2020;8(11):e18907. doi: 10.2196/18907Appel L, Kisonas E, Appel E, Klein J, Bartlett D, Rosenberg J, Smith CN. Administering Virtual Reality Therapy to Manage Behavioral and Psychological Symptoms in Patients With Dementia Admitted to an Acute Care Hospital: Results of a Pilot Study. JMIR Form Res. 2021;5(2):e22406. doi: 10.2196/22406Gadzhiev N, Semeniakin I, Morshnev A, Alcaraz A, Gauhar V, Okhunov Z. Role and Utility of Mixed Reality Technology in Laparoscopic Partial Nephrectomy: Outcomes of a Prospective RCT Using an Indigenously Developed Software. Adv Urol. 2022;2022:8992051. doi: 10.1155/2022/8992051Barteit S, Lanfermann L, Bärnighausen T, Neuhann F, Beiersmann C. Augmented, Mixed, and Virtual Reality-Based Head-Mounted Devices for Medical Education: Systematic Review. JMIR Serious Games. 2021;9(3):e29080. doi: 10.2196/29080Airhihenbuwa CO, Tseng TS, Sutton VD, Price L. Global Perspectives on Improving Chronic Disease Prevention and Management in Diverse Settings. Prev Chronic Dis. 2021;(18):E33. doi: 10.5888/pcd18.210055Wang N, Li X, Wang R, Ding Z. Spatial transcriptomics and proteomics technologies for deconvoluting the tumor microenvironment. Biotechnol J. 2021;16(9):e2100041. doi: 10.1002/biot.202100041Davitte JM, Stott-Miller M, Ehm MG, Cunnington MC, Reynolds RF. Integration of Real-World Data and Genetics to Support Target Identification and Validation. Clin Pharmacol Ther. 2022;111(1):63—76. doi: 10.1002/cpt.2477Mousaei Ghasroldasht M, Seok J, Park HS, Liakath Ali FB, Al-Hendy A. Stem Cell Therapy: From Idea to Clinical Practice. Int J Mol Sci. 2022;23(5):2850. doi: 10.3390/ijms23052850Koski E, Murphy J. AI in Healthcare. Stud Health Technol Inform. 2021;(284):295—299. doi: 10.3233/SHTI210726Cavaliere C, Damiao J, Pizzi M, Fau L. Health, Well-Being, and Health-Related Quality of Life Following COVID-19. OTJR (Thorofare N J). 2023;43(2):188—193. doi: 10.1177/15394492221111733Vitorino LM, Sousa LMM, Trzesniak C, de Sousa Valentim OM, Yoshinari Júnior GH, José HMG, Lucchetti G. Mental health, quality of life and optimism during the covid-19 pandemic: a comparison between Brazil and Portugal. Qual Life Res. 2022;31(6):1775—1787. doi: 10.1007/s11136-021-03031-9