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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Bulletin of Semashko National Research Institute of Public Health</journal-id><journal-title-group><journal-title>Bulletin of Semashko National Research Institute of Public Health</journal-title></journal-title-group><issn publication-format="print">2415-8410</issn><issn publication-format="electronic">2415-8429</issn><publisher><publisher-name>FSSBI «N.A. Semashko National Research Institute of Public Health»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">3078</article-id><article-id pub-id-type="doi">10.69541/NRIPH.2025.04.008</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>The principle of diagnostic-related groups in the healthcare system of the Kyrgyz Republic</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Azimzhanova</surname><given-names>Medina Nizamedinovna</given-names></name><bio></bio><email>kalievmar@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kaliev</surname><given-names>Marat Temirbekovich</given-names></name><bio></bio><email>002</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Imankulova</surname><given-names>Asel Sansy`zbaevna</given-names></name><bio></bio><email>003</email><xref ref-type="aff" rid="aff-2"/><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff id="aff-1">National Institute of Public Health under the Ministry of Health of the Kyrgyz Republic, Bishkek, Kyrgyz Republic</aff><aff id="aff-2">Peoples' Friendship University of Russia, Moscow, Russian Federation</aff><aff id="aff-3">Salymbekov University, Bishkek, Kyrgyz Republic.</aff><pub-date date-type="epub" iso-8601-date="2025-11-29" publication-format="electronic"><day>29</day><month>11</month><year>2025</year></pub-date><issue>4</issue><fpage>49</fpage><lpage>54</lpage><history><pub-date date-type="received" iso-8601-date="2025-12-01"><day>01</day><month>12</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2025,</copyright-statement><copyright-year>2025</copyright-year></permissions><abstract>The paper analyzes the development of the Clinical Cost Groups (DRG) system in the Kyrgyz Republic as a key instrument for inpatient care financing. The study covers the period from 1997 to the present and is based on anonymized data from the CHIF Treated Case database (2.87 million hospital episodes, 2015—2018). Cost weights (CW) were calculated, and independent clustering was applied to assess clinical homogeneity. The overlap between natural clusters and assigned DRGs exceeded 80 %, confirming the model’s validity. Case examples from respiratory diseases and obstetrics show alignment between CW and national clinical guidelines. The introduction of new surgical and non-surgical classifiers (2020—2021) improved coding accuracy and cost analysis. Integration of DRGs into the CHIF tariff formula enabled a shift to clinically and economically justified hospital payment mechanisms.</abstract><kwd-group xml:lang="en"><kwd>inpatient medical care, clinical and statistical groups, clinical and related groups, clinical and cost groups, healthcare financing, treated case</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>стационарная медицинская помощь, клинико-статистические группы, клинико-родственные группы, клинико-затратные группы, финансирование здравоохранения, пролеченый случай</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Klein A., Mathauer I., Stenberg K., Habicht T. Diagnosis-related groups (DRG): A question &amp;amp; answer guide on case-based classification and payment systems. Geneva: World Health Organization; 2020.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Bredenkamp C., Bales S., Kahur K. 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