This article provides a comprehensive study of the medical and hygienic aspects reflected in the text of the «Domostroy» — an outstanding monument of Russian literature from the 16th century. Based on a detailed textological analysis, the system of sanitary norms, practices of bodily and domestic cleanliness, food safety, and disease prevention is examined. Particular attention is paid to the reconstruction of proto-medical views and their integration into the religious and moral paradigm of medieval society. The research introduces previously unsystematized data on the sanitary and hygienic regulations contained in the text, which constitutes its novelty. The entire text is divided into 64 chapters. Individual hygienic and medical aspects can be traced in no less than ten of them. The study demonstrates how religious attitudes shaped practical approaches to health preservation, creating a comprehensive system of hygienic practices relevant to the daily life of Muscovite Rus'.

Domostroy, history of medicine, hygienic practices, sanitary norms, medieval Rus', domestic practices, religious ethics, disease prevention..