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Internet survey — a new way to study the tolerability of antidepressants
- Authors: Drobizhev M.Y.1, Polskaya E.A.2
- Affiliations:
- N. A. Semashko National Research Institute of Public Health, 105064, Moscow, Russian Federation
- Federal State Budgetary Scientific Institution «Scientific Center of Neurology», Moscow, Russian Federation
- Issue: No 2 (2026)
- Pages: 85-89
- Section: Articles
- URL: https://bulleten-nriph.ru/journal/article/view/3187
- DOI: https://doi.org/10.69541/NRIPH.2026.02.014
- Cite item
Abstract
A survey of viewers of the @psyhfarm-tv YouTube channel (108,000 subscribers) revealed that the mechanism of action (serotonin reuptake inhibition, serotonin and norepinephrine reuptake inhibition, receptor antagonism and/or agonism) of 17 antidepressants influences patient assessments of their tolerability. This assessment worsens with the number of neurons (especially histamine and acetylcholine) affected by the antidepressant, as well as the number of mechanisms of action.
About the authors
Mikhail Yuryevich Drobizhev
N. A. Semashko National Research Institute of Public Health, 105064, Moscow, Russian Federation
Email: dmyu2001@mail.ru
Elena Alexandrovna Polskaya
Federal State Budgetary Scientific Institution «Scientific Center of Neurology», Moscow, Russian Federation
Email: polskaya@neurology.ru
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