The article examines the anatomical and physiological aspects of workplace design in order to preserve health, increase labor productivity and improve the quality of life of employees. The key anatomical and physiological features of a person, such as the structure of the spine, joints, organs of vision, nervous and respiratory systems, which must be taken into account when organizing the
workplace, are analyzed. Special attention is paid to the ergonomic approach aimed at creating a comfortable and safe working environment. The study substantiates the importance of using adaptive solutions, such as adjustable work surfaces, ergonomic chairs, correct lighting and regular breaks, to prevent occupational diseases and reduce the physical and psychological burden on employees. The presented conclusions and recommendations are based on an analysis of current data, statistics and international experience.