Estimation of the relationship between the mechanism of action of antidepressants and their effectiveness and tolerability (results of an online survey)

Abstract


survey of viewers of the @psyhfarm-tv YouTube channel (89,000 subscribers) on the effectiveness and tolerability of 17 antidepressants showed that selective serotonin reuptake inhibitors, according to respondents, are more likely to help and are well tolerated., Serotonin and norepinephrine reuptake inhibitors were less likely to not help, and receptor-acting antidepressants were more likely to not help than other drugs. Groups of antidepressants with different mechanisms of action differ significantly in effectiveness and tolerability.


About the authors

Mikhail Yu. Drobizhev

N. A. Semashko National Research Institute of Public Health

Author for correspondence.
Email: dmyu2001@mail.ru
ORCID iD: 0000-0002-1536-219X

Russian Federation, 105064, Moscow, Russian Federation

Elena A. Polskaya

Federal State Budgetary Scientific Institution «Scientific Center of Neurology»

Email: polskaya@neurology.ru
ORCID iD: 0009-0000-1451-860X

Russian Federation, Moscow, Russian Federation

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